Looking for bus tickets from Rome to Isernia?
Look no further, we’ve got all the details you need to plan your bus trip!
The journey Rome to Isernia takes as little as 2 hours 35 minutes and can cost as little as 10,98 €. The first bus leaves at 05:50 and the last bus leaves at 13:00.
FlixBus runs 2 rides each day between Rome and Isernia and when travelling with FlixBus, you can expect free Wifi, power sockets and a guaranteed seat for your journey.